Discovery and development of cancer treatments (e.g. radiotherapy, chemotherapy, cell-directed targeted therapy, immune therapy) require PK/PD modelling for robust experimental design and unambiguous data interpretation.
This short course will introduce how translational PK/PD modeling for chemotherapy and cell-directed targeted therapy can be used to relate preclinical data with clinical response. We will also discuss the basics of PK/PD modelling that are relevant to evaluating novel immuno-oncology treatments. It will help attendees to learn about dose selection, estimation of therapeutic window, and translational sciences based on PK/PD modeling.
PK/PD Modeller & Data Scientist
Beyond Consulting Ltd
Recent breakthroughs involving humanized mice have elevated the translational quality of these models within preclinical research. As such these models have become highly relevant for fundamental research to understand the function of the human immune system and in assessing cancer immunology and immunotherapies.
This workshop will explore the different strategies of immune system humanization in mice as well as to review challenges, insights, and future directions for mouse and humanized models within oncology.
Topics to be covered:
University Hospital of Zurich