Pre-Conference Workshop Day

Tuesday, 14th December 2021

Workshop A: The Best Mouse Models for Cancer Research: Which One to Use

10.00 - 12.30

Preclinical tumour models are getting closer to in-human conditions, but are still a long way off – leading to large disparities between the modelled results and what we see in patients. Here we will explore the best mouse models for cancer research to progress your oncology candidate. Understand the tools you can use to provide robust data, boost translational confidence and improve the predictability of our current models.

In this workshop, we will explore the best-in-class methods to improving our predictions and getting the most from our preclinical models. Including a close look at:

• Genetically engineered mouse models (GEMM)
• PDX
• Orthotopic models

Chiara Ambrogio Uni o Turin

 

Workshop Leader

Chiara Ambrogio
Assistant Professor of Molecular Biology
University of Turin

Workshop B: Patient-Derived Tumour Models for Personalised Therapeutics in Urological Cancers

10.00 - 12.30

With the complex human physiology and individual genome make-up, personalised and precision oncology are becoming more and more important. Personalised tumor models, such as tissue explants, organoids and PDX, will continue to play a crucial role to help us understand treatment response and select best treatment options.

This workshop will discuss the latest in personalised models for preclinical oncology studies and how they can be leveraged in your pipeline. We will address the contribution and translational value of preclinical patient-derived models including:

• 3D culture models
• Organotypic tissue slices
• Patient-derived xenograft models

 

Geetje van der Horst

Workshop Leader

Geertje van der Horst
Senior Scientist Leiden University
Medical Center