Deciphering Distinct Tumour Life Histories In Vivo with Somatic Transgenic Evolving Barcodes & Single-Cell Sequencing

Time: 11:40 am
day: Day Two


  • How can genetic barcodes deconvolute the patterns of progression of different tumour types?
  • Detection of Clonal sweeps versus other patterns of evolution
  • Could this have the capacity to inform clinical standard-of-care or predict clinical success
  • Discussion of future applications of the method
  • Lessons learnt from technical challenges (germ line recombination, low barcode recovery issues, and the requirement of computational biology expertise)