Optimising clinical therapeutic window using modelling and simulation, validating with nonclinical translational models and utility in an ongoing clinical study

Time: 5:05 pm
day: Day Two


  • An example of a cross-functional collaboration between clinical and non-clinical functions enabling dose and schedule optimisation for clinical testing
  • Illustrates the importance of translational understanding in light of increasing probability of successful drug development
  • Highly relevant considering recent regulatory moves towards optimisation of clinical dose and schedule.