Understanding Gene Signatures if Macrophage Activation to Access Immunological Memory
Time: 5:35 pm
day: Day Two
Details:
- Bone marrow and spleen monocytes represent the main source of Tissue Macrophages in infection and malignancy
- Monocyte derived macrophage activation programmes are plastic and single biomarkers are not adequate to characterise their activation
- Gene signatures enable to understand the activation history of cells and point tophenotypic mosaicism in complex milieus such as tumours
