Dr. Michael Brehm

Dr. Michael Brehm

Company: University of Massachusetts Medical School

Job title: Associate Professor, The Robert and Sandra Glass Term Chair in Diabetes, Diabetes Center of Excellence, Program in Molecular Medicine


Dr. Brehm has over 25 years of experience in biomedical research with an extensive knowledge of immunological responses to infection agents and to transplantation with non-self tissues. He received his Ph.D. in 1999 from the Department of Microbiology and Immunology at the Pennsylvania State University College of Medicine. During Dr. Brehm’s post-doctoral training at the University of Massachusetts Medical School (UMMS), he investigated how sequential viral infections impact the ability of a host to generated protective immunity and how viral infections influence transplantation tolerance that is induced by costimulation blockade. In 2008, he joined the Diabetes Division at the UMMS to develop cutting edge mouse models to study human biology. Dr. Brehm is currently an Associate Professor in the Program in Molecular Medicine at the UMMS and a member of the Diabetes Center of Excellence. He is also the recipient of The Robert and Sandra Glass Term Chair in Diabetes. Dr. Brehm’s research program is focused on understanding how human effector T cells are regulated in the context of auto-immune disease, allo-immunity, tumor immunity. His laboratory is developing “humanized” mice to more effectively study human T cell biology, and he is the Co-Director of the UMMS Humanized Mouse Core. Dr. Brehm has published over 110 manuscripts and reviews and is supported by funding from the JDRF, NIH and The Glass Charitable Foundation.

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