Fernando Estrada

Fernando Estrada

Company: University of Surrey

Job title: Lecturer in Innate Immunology

Seminars:

Understanding Gene Signatures if Macrophage Activation to Access Immunological Memory 5:35 pm

Bone marrow and spleen monocytes represent the main source of Tissue Macrophages in infection and malignancy Monocyte derived macrophage activation programmes are plastic and single biomarkers are not adequate to characterise their activation Gene signatures enable to understand the activation history of cells and point tophenotypic mosaicism in complex milieus such as tumoursRead more

day: Day Two

Panel Discussion: How to Predict Your Immuno-Modulation & Immuno-Stimulatory Response? 3:25 pm

The potential of using IO, combinational or cell therapy to dial up another biologic to aid in the anti-tumour response. Could this be the next phase of development for immuno-oncology and what are the potential limitations of this approach? This panel will discuss: Methods of stimulating/dialling up a biologic Understanding of the differences between alternate…Read more

day: Day Two

Panel Discussion: Cutting Cancer Off At The Knees: Analysing the Preclinical Potential of Reprogramming/Repolarising Pro-Tumour Immune Cells 5:00 pm

The aggression of tumours is hugely linked with tumour survival mechanisms resulting in high-grade tumours. Assessing the implication of suppressor cells on the progression of tumours. Tumour-associated macrophages (TAMs) make up around 50% of the solid mass in a variety of human solid cancers (e.g., lung, breast and pancreatic) which are polarised into the M2…Read more

day: Day One

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