Characterising & Optimising Humanised Mouse Models to Empower Gamma-Delta Therapy Development
- Addressing the limitations of traditional mouse models for gamma-delta T cell studies and strategies for identifying or developing humanised mouse models
- Optimising experimental variables—such as cell source, transfer method, and tumour type—to align with specific therapeutic objectives, from efficacy assessment to immune profiling
- Implementing robust, foundational assays to evaluate gamma-delta T cell presence and activity following therapeutics, ensuring reliable data generation and efficient model characterisation