Exploring the Translational Validation of ADCC-Inducing Antibodies Using Humanised Models & Clinical Biomarker Integration
- Applying wt and humanised in vivo platforms to assess therapeutic performance of ADCC-inducing antibodies across solid and liquid tumour types, including CLL
- Identifying and validating biomarkers from head and neck cancer patient datasets, with correlation to preclinical mouse models
- Leveraging humanised mice to bridge mechanistic insights and clinical relevance, supporting the development of targeted immunotherapies with translational impact