Patient-Derived Tumour Spheroids to Model the Tumour Microenvironment & Accelerate Drug Development
- Applying patient-derived tumour spheroids to model the tumour immune microenvironment including T cell infiltration and function, tumour fibrosis, CAF and endothelial cell biology
- Modelling the specific treatment response of compounds on the patient tumour immune environment and cancer epithelial cells using single cell RNASeq and proteomics
- Understanding how patient-derived tumour spheroids accelerate drug development using liver and pancreatic cancer as examples