Claudio Murgia
Head of Target and Disease Biology pRED Roche
Dr. Murgia is a cancer biologist with over 15 years of experience in preclinical and translational research. Earlier in his career, he was a Wellcome Trust Clinical Fellow specializing in comparative oncology. He previously led Roche’s Precision Cancer Modelling and In Vivo Pharmacology group, where he established highly translational cancer models. Since October 2024, he has been leading multidisciplinary teams that integrate computational and experimental biology, with a focus on functional genomics and organoid systems to accelerate therapeutic strategies. He earned his Ph.D. in Molecular Pathology from UCL and completed a clinical fellowship at the Institute of Comparative Medicine, University of Glasgow.
Seminars
- Hybrid submissions – will they become the new standard or the new normal?
- Balancing in vivo versus in vitro and 3D in model selection
- Debunking the role of in vivo models and non-animal tests to inform future clinical trial design
- Leveraging patient-derived organoids (PDOs) and genetically engineered mouse model (GEMM)-derived organoids to enhance the predictive power of cancer immunotherapy studies
- Overcoming technical and biological hurdles in the development of relevant advanced stage and metastatic mouse models to better mimic human disease progression
- Integrating experimental biology with computational modelling to align preclinical outputs with clinical datasets, facilitating the creation of predictive in silico frameworks for translational oncology
