Applying Reverse Translation to Improve Predictive Models for Next Generation CAR-T Development
1:10 pm - Thursday 3rd December 2026
- Using clinical learnings from advanced ex vivo CAR-T programmes to identify limitations in existing preclinical models and improve future model design
- Understanding how efficacy, persistence, resistance, and safety observations can be translated back into preclinical systems to strengthen development strategies
- Creating continuous feedback loops between clinical, translational, and preclinical teams to improve confidence in ex vivo and in vivo CAR-T progression decisions
