A Translational Approach to Evaluate T Cell Engagers & Bispecific Antibodies in Humanised Animal Models
- Development of Co-inoculated tumour/PBMC animal models to assess the efficacy and immune-mediated mechanisms of T Cell Engagers and Bispecific Antibodies
- Application of a humanised miniPDX platform to evaluate TCE in fresh patient-derived samples from multiple myeloma and SLE
- Establishment of clinically relevant animal models to support candidate selection and optimisation for next generation TCE therapies