Gene Expression Signatures of Tumor Immunogenicity and Cellular Proliferation from Murine Cancer Models, In Vitro and In Vivo

Time: 9:50 am
day: Conference Day Two


  • We successfully correlated the murine cell line gene expression data with the gene signatures used to generate tumor immunogencity score (TIGS) and cellular proliferation (CP) scores from human clinical data.
  • RNA sequencing on in vitro and in vivo samples from syngeneic mouse models revealed marked differences in expression of genes involved in immunogenicity and cellular proliferation.