Rose Ann Padua

Company: INSERM

Job title: Director

Seminars:

Overcoming Resistance & Exploring Treatment Strategies in MDS/AML 9:30 am

• Identifying the specific challenges associated with modelling MDS and their impact on translatability to the clinic • Presenting findings from NRASD12/BCL-2 mouse models of HR-MDS/AML demonstrating the ability to overcome resistance to Venetoclax, a BCL-2 inhibitor, by utilizing a Mek inhibitor • Presenting recent findings from the newly established RAS/p53R172H model of AML, highlighting…Read more

day: Conference Day One

Topic: Mouse Models (CDX, PDX & more) 10:46 am

• Reviewing the reasons and context for use • Spotlighting methods to optimize translatability to patients • Determining analysis strategies for combination efficacy and safetyRead more

day: Conference Day One